Unesco defined Jesi, for its capacity to preserve a century-old architectural, cultural and artistic heritage, both charming and enchanting. http://www.turismojesi.it
Very interesting places are easy to reach: historic towns/villages (Recanati, Corinaldo, Ostra, Osimo, Cingoli, Loreto), the Conero Riviera protected ecological area - Regional Park - with crystal clear water beaches, many trails and several archeological/historical sites (Sirolo, Portonovo, Numana), Frasassi karst caves, rolling hills and relaxing places all around. Two thirds of the region is covered in gently hills. Excellent food and wine.
There are so many places to visit in our region Marche. Urbino, Gradara, Ascoli Piceno are also, for example, well worth a visit.
For a long-term holiday please consider that you can also reach Rome, Florence (and Toscana), Venice in about 3 hours.